Undefeated pro boxer
Mayweather (43-0, 26 knockouts) is a 7-1 favorite over Guerrero (31-1-1, 18 KOs).
A few think Mayweather might get a better fight from Guerrero's father, Ruben, who made a spectacle of himself at the pre-fight news conference on Wednesday.
"We're going to beat up the woman beater," Ruben Guerrero said. "He must've learned that from his old man. He beat up his wife right in front of his kids."
So, who is going to win? Mayweather? Guerrero? A draw? Vote in our poll and let us know what you think.