The Wildcats improved to 17-0 overall and 4-0 in
The Trojans gave Arizona a handful for the first 15 minutes of the game, and USC led, 27-23, with about five minutes left in the first half.
But Arizona then took control of the game with a swarming defense near the basket that held USC to its fewest points so far this season.
The Wildcats also were led by the shooting of T.J. McConnell, with the junior guard converting five of his seven three-point attempts and scoring 19 points overall.
Forward Brandon Ashley also had 19 points for Arizona.
USC also suffered from poor ball control, committing 18 turnovers compared with eight for the Wildcats.
Junior guard Byron Wesley led the Trojans in scoring with 18 points.