Jonathan Cooper

Patriots win in Jimmy Garoppolo's first start

Patriots win in Jimmy Garoppolo's first start

No Tom Brady. No Rob Gronkowski. No room for error against one of the NFL’s best teams in one of the least hospitable stadiums.

No problem. Not for New England’s Jimmy Garoppolo.

The third-year quarterback, starting in place of the suspended Brady and playing without his full complement of offensive weapons, led the Patriots to a 23-21 upset of the Arizona Cardinals on Sunday night before a packed house at University of Phoenix Stadium.

Showing uncommon poise for a player with relatively little experience, and playing against a stifling defense, Garoppolo threw for 264 yards and a touchdown — even completing a batted pass to himself — as...