Scientists Make Slim Mice Via Genes
From Times Staff and Wire Reports
Surprisingly skinny mice created in a Seattle genetics lab may offer hints at why some people can eat all they want and still stay thin. Researchers have found that with a single genetic alteration, they can turn up a natural metabolic furnace in mice so the animals burn more fat. Experts said people might eventually be able to control their weight by doing the same thing, or by exploiting related processes. Mice with the mutation have about 6% body fat, compared to about 15% in their unaltered brethren. But even more impressive, the genetically altered mice can eat a high-fat diet without ill effects.
