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Diet Alone Found to Lower Blood Pressure

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TIMES MEDICAL WRITER

A diet rich in fruits, vegetables and low-fat dairy products can reduce blood pressure as much as the most commonly used hypertension drugs, eliminating the need for expensive drugs in many patients with mild hypertension, according to a major multicenter study published today.

Previous studies had shown that reducing weight, lowering salt consumption and minimizing alcohol use could also reduce blood pressure. But the new study, published in the New England Journal of Medicine, is the first to show that changing the overall diet will reduce blood pressure independently of those other factors.

Widespread adoption of the combination diet, the team said, could potentially reduce the risk of heart disease by 15% and the likelihood of stroke by 27%.

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“With nearly 50 million Americans having hypertension, and considering the billions of dollars spent each year on blood pressure medications, these findings have important public health considerations,” said Dr. George Blackburn, president of the American Society for Clinical Nutrition.

“This is one of the best pieces of news for people in this country in a long time,” said Dr. David A. McCarron of the Oregon Health Sciences University. “We’ve never had a dietary intervention that gives this kind of effect in terms of improving life expectancy.”

The study was not designed to identify which components of the diet were responsible for its beneficial effects, but McCarron and others speculate that the calcium in milk may confer the greatest blood pressure-lowering benefits. Many blood pressure drugs, such as diuretics and calcium-channel blockers, work by increasing calcium retention.

“It’s reasonable to assume that the dairy products in the diet are doing the same thing,” McCarron said.

“This has important implications for the African American community,” he said.

Blacks have two to three times the normal level of hypertension and consume fewer dairy products than Caucasians, he said.

“This is also important for men, who have more hypertension than women,” he added. “Most men are not getting enough calcium, and they need to get serious about it. Even if they don’t worry about their bones, they should start worrying about their hearts.”

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“We already know that salt consumption, alcohol and body weight have an effect on blood pressure,” said Dr. Ronald M. Krauss of UC Berkeley, a member of the American Heart Assn.’s nutrition committee. “The most exciting thing about the [new] results is that diet apart from these three factors can lower high blood pressure.”

High blood pressure is one of the primary risk factors for heart attacks and stroke. According to the American Heart Assn., at least 24% of Americans have blood pressure greater than the ideal level of 120/80. Four out of every five of those have moderate hypertension, meaning that their blood pressure is between 160/95 and 120/80.

The trial, called Dietary Approaches to Stop Hypertension, was sponsored by the National Institutes of Health. The team enrolled 459 people with blood pressures below 160/95--about two-thirds with moderate hypertension and one-third with borderline normal blood pressure--at centers in Baltimore, Boston, Durham, N.C., and Baton Rouge, La. Almost half were women and 59% were black. None were taking medications to control their blood pressure.

Participants received all their food from the study for 11 weeks, and on weekdays, they ate their main meal at the clinics to ensure compliance. For the first three weeks of the study, each participant received a “typical American” control diet, then was randomly assigned to one of three groups.

One group continued to receive the control diet; one received a diet rich in fruits and vegetables; and one received the combination diet, rich in fruits, vegetables and low-fat dairy products and reduced in saturated fat. All diets contained the same amount of salt.

The effects of the diet were obvious within one week and reached their maximum value within two weeks. Blood pressures then remained stable for the final six weeks.

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Among all the subjects, the fruit and vegetable diet reduced blood pressure an average of 2.8/1.1 compared to the control diet, while the combination diet reduced it an average of 5.5/3.0.

Among those with moderate hypertension, the average reduction from the combination diet was 11.4/5.5, independent of race and sex.

“These blood pressure reductions are clinically important because they are similar to those reductions commonly achieved through use of [diuretic medications],” the most common treatment for moderate hypertension, said Dr. Lawrence Appel of Johns Hopkins University, the lead author of the study.

The diet could therefore represent an important alternative to drug treatment for people willing to comply with it, he said.

Full details of the study and the diet are available on the Internet at https://dash.bwh.harvard.edu.

(BEGIN TEXT OF INFOBOX / INFOGRAPHIC)

Eating Right

Here is a guide to the suggested number of servings from each food group, based on a daily requirement of 2,000 calories. The number of servings may vary depending on age, gender, weight and physical activity.

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* 7-8 daily servings of grains and grain products

* 4-5 daily servings of vegetables

* 4-5 daily servings of fruits

* 2-3 daily servings of low-fat or nonfat dairy foods

* 1-2 daily servings of meat, poultry and fish

* 4-5 weekly servings of nuts, seeds and legumes

* Limited servings of fats and sweets

Source: Dietary Alternatives to Stop Hypertension working group

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