MSM touted as a varied pain reliever

The sulfur-containing compound methylsulfonylmethane (MSM) is naturally found in tiny amounts in the body. It also occurs in many plants and animals; the best source of it is cow’s milk. MSM supplements are often synthesized from dimethyl sulfoxide (DMSO), a potent-smelling solvent whose medicinal powers MSM is purported to share. DMSO is approved by the Food and Drug Administration to treat a rare bladder disease, and it’s also sometimes used to treat arthritis pain.

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Uses: MSM is taken most often for pain associated with a long list of conditions, including osteoarthritis, rheumatoid arthritis, bursitis, lupus, fibromyalgia, headaches and repetitive stress, sports and back injuries. The supplements are sometimes used in efforts to cure insomnia, diabetes, allergies, asthma, compromised immunity and cancer.

Dose: Usually, 1.5 to 3 grams a day. MSM is sold alone and in multi-ingredient supplements, in the form of capsules, crystals and lotions.

Precautions: MSM may have laxative effects and cause headaches or stomach pain. Little is known about its long-term safety or its safety in women who are pregnant or breastfeeding.

Research: Animal studies on tumor growth have produced mixed results. Results from laboratory experiments suggest that there may be similarities between MSM’s activity and that of aspirin. Limited findings from human studies show the supplement may have some effect on arthritis pain and allergic rhinitis, but overall there’s slim evidence in support of its many uses.

Dietary supplement makers are not required by the U.S. government to demonstrate that their products are safe or effective. Ask your healthcare provider for advice on selecting a brand.

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-- Elena Conis