Little is known about resveratrol’s benefits

The compound resveratrol is produced by some plants to fight fungi and help heal injuries. It’s found in high concentrations in peanuts, mulberries, grape skins, wine (particularly red wine) and the Japanese knotweed plant. When scientists first identified the low risk of heart disease among the red-wine-

drinking French several years ago, some attributed the phenomenon to the strong antioxidizing powers of resveratrol. Most resveratrol supplements now on the market contain extracts from the Japanese knotweed, or Polygonum cuspidatum.

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Uses: In Eastern medicine, Japanese knotweed is used to improve circulation and heart health. As a supplement, resveratrol is used to prevent heart disease and reduce the risk of cancer.

Dose: Manufacturers recommend about 15 to 300 milligrams a day. A glass of red wine contains less than 1 milligram of the compound.

Precautions: Few side effects have been reported, but because so little is known about resveratrol supplements, they are not recommended for children or pregnant women.

Research: Lab studies suggest resveratrol may prevent the growth of tumors, protect against herpes simplex viruses and stimulate the immune system. Animal and lab studies suggest that large amounts of the compound can reduce the likelihood of developing heart disease. Researchers from the Medical University of South Carolina announced earlier this month that, based on evidence from volunteers, resveratrol appeared unlikely to protect against breast and prostate cancers.

Dietary supplement makers are not required by the U.S. government to demonstrate that their products are safe or effective. Ask your healthcare provider for advice on selecting a brand.

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-- Elena Conis