| Estimated sales in the U.S. and Canada: |
| Movie (studio) | 4-day gross (millions) | Percentage change from last weekend (3-day basis) | Total (millions) | Days in release |
|
| 1 | Valentine’s Day (Warner Bros./New Line) | $66.9 | NA | $66.9 | 4 |
|
| 2 | Percy Jackson & the Olympians: The Lightning Thief (Fox/Dune/Ingenious) | $38.8 | NA | $38.8 | 4 |
|
| 3 | The Wolfman (Universal/Relativity) | $36.5 | NA | $36.5 | 4 |
|
| 4 | Avatar (Fox/Dune/Ingenious) | $30 | +3% | $667.6 | 60 |
|
| 5 | Dear John (Sony/Relativity) | $18.8 | -47% | $56.7 | 11 |
|
| 6 | The Tooth Fairy (Fox/Walden) | $7.7 | -8% | $43.6 | 25 |
|
| 7 | From Paris With Love (Lionsgate/Europa) | $6.8 | -32% | $17.9 | 11 |
|
| 8 | Edge of Darkness (Warner Bros./GK Films) | $5.7 | -30% | $37.2 | 18 |
|
| 9 | Crazy Heart (Fox Searchlight) | $5 | +18% | $17.5 | 60 |
|
| 10 | The Book of Eli (Warner Bros./Alcon) | $4.4 | -23% | $88.4 | 33 |