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Science / Medicine : Crib Death, Oxygen Linked

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<i> From Times staff and wire reports</i>

Two Norwegian doctors say they have proved that victims of sudden infant death syndrome, or crib death, die from a lack of oxygen.

The researchers, Torleiv Ole Rognum and Ola Didrik Saugstad, found unusually large amounts of a chemical called hypoxantin in the eye fluid of infants who have died in this way. The body’s hypoxantin rises sharply if oxygen is reduced significantly.

Their research, completed a year ago, showed concentrations of the chemical were six times higher in infants who had suffered crib death than in those who died from other known causes.

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“This supports one of the many theories about crib death--that it has something to do with respiratory problems--and discounts a number of others,” Rognum said.

Their findings were published this month in the U.S. medical journal Pediatrics.

In a separate report, U.S. health officials said that sudden infant death syndrome continues to be a leading cause of premature mortality.

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