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San Rafael-based Autodesk Inc. completed its acquisition of Softdesk Inc. after striking an agreement to resolve federal antitrust concerns about the combination of competitors in the market for computer-aided design software. The companies agreed to sell a key Softdesk software program to another company, protecting competition in the market for design software used architecture and engineering industries. . . . La Jolla Pharmaceutical Co. of San Diego said President and Chief Executive Steven Engle was elected chairman, replacing Joseph Stemler.