Vanadium salt used to treat diabetes

Vanadyl sulfate is one of the element vanadium’s colorful forms, and it is sometimes called a vanadium salt. Vanadium (atomic No. 23) is an “ultratrace” mineral. Humans need it in tiny amounts, about five to 10 micrograms a day. The element is found in whole grains, shellfish, mushrooms, black pepper, parsley and soy. In the 19th century, vanadium salts were first explored as a treatment for diabetes.

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Uses: Some people use it to treat diabetes, increase muscle mass and lower cholesterol.

Dose: Vanadyl sulfate comes in capsules and tablets. Manufacturers recommend doses of 10 to 100 micrograms.

Precautions: Large doses (several hundred micrograms a day or more) may cause nausea, vomiting, cramps and diarrhea. Such doses may also turn the tongue a greenish color. People with diabetes or hyperglycemia should consult their doctors before using vanadyl sulfate supplements.

Research: Research doesn’t support claims that vanadyl sulfate increases muscle mass. The supplements may help people with Type 1 or 2 diabetes. Animal studies suggest that vanadyl sulfate can regulate blood sugar when taken in large doses. The few studies in humans with diabetes have demonstrated similar effects, but indicate that not all patients with Type 2 diabetes respond to the mineral. Human studies also show that very large doses are needed -- about 1,000 times the normal dietary intake. Current research is attempting to confirm whether such large doses are safe and reliably effective.

Dietary supplement makers are not required by the U.S. government to demonstrate that their products are safe or effective. Ask your healthcare provider for advice on selecting a brand.

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-- Elena Conis