More study needed on nasal capsaicin

Q: Can you comment on the efficacy and safety of nasal capsaicin (Sinus Buster, Sinol-M) for rhinitis, sinusitis or sinus headache?

A: Capsaicin is the hot substance that gives chiles their kick. Even in dilute concentrations, it can sting for a while. This seems to deplete a natural body chemical called substance P, which is critical for the perception of pain.

Although capsaicin is used in liniments or rubs for sore muscles and joints, it is less common in nasal sprays. Italian researchers found that it could be useful for reducing runny-nose (rhinitis) symptoms (Acta Oto-Laryngologica, April 2009).

It also has been tested for relieving migraine or cluster headaches and seems to be modestly effective (Archives of Neurology, June 2002). We’d like to see bigger, better studies of capsaicin nasal sprays before endorsing them for sinus problems or headaches.

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Q: I have high blood pressure (145/95). My doctor and I are trying to find a medicine that agrees with me. I’m currently trying the third one. The first was an ACE inhibitor that made me cough. Then I tried Norvasc (amlodipine) and Cardizem (diltiazem). They made me drowsy during the day even when taken at night.

Isn’t there a new drug that’s better?

A: You may want to ask your doctor about a thiazide diuretic such as hydrochlorothiazide or chlorthalidone. Such drugs have been around for more than 50 years but are still considered a first-line treatment for high blood pressure.

Joe Graedon is a pharmacologist, and Teresa Graedon is an expert in medical anthropology and nutrition. www.peoples pharmacy.com