Set on more than an acre, the just-remodeled house features a formal entry, a grand living room surrounded by garden-view windows, dining and family rooms, a den, five bedrooms, six bathrooms and nearly 6,000 square feet of living space. The updated kitchen has a large island, custom cabinetry, marble surfaces and hand-painted tile. A guest suite sits above the garage
The flat yard has a swimming pool with a spa, an outdoor kitchen/barbecue, mature trees and three lawn areas.
Ackles, 36, has played demon-hunting brother Dean Winchester since the series started in 2005. Before that he was in "Smallville" (2004-05) and "Still Life" (2003-04).
Harris, 35, was in the series "Friends With Benefits" (2011) and "One Tree Hill" (2005-09). More recently she starred in the TV movies "Baby Bootcamp," "Naughty or Nice" and "One Tree Hills: Always & Forever."
The property last sold two years ago for $4.8 million, according to the Multiple Listing Service.
Shen Schulz of Sotheby's International Realty is the listing agent.