Robert Tisch, co-owner of the New York...

Robert Tisch, co-owner of the New York Giants and a civic leader in New York City for several decades, died Tuesday of brain cancer. He was 79.

Tisch died at his home, a family publicist said.

Three weeks ago on Oct. 25, the Giants’ other co-owner, Wellington Mara, also died of cancer. Mara was the son of team founder Timothy J. Mara.

Tisch bought 50% of the Giants in 1991 from Tim Mara, Wellington Mara’s nephew, not long after the Giants beat Buffalo in the Super Bowl.

Tisch also was U.S. postmaster general from 1986 to ’88 and chairman and director of Loews Corp., a company he and his late brother, Laurence Tisch, had purchased in 1959 when it was a movie theater chain.

Tisch was diagnosed with an inoperable brain tumor in 2004 and had curtailed his regular visits to practices and games.

During his illness, his son, Steve Tisch, was named the Giants’ executive vice president and took on a larger role in the operations of the team, particularly in the negotiations between the Giants and the state of New Jersey over a new stadium at the Meadowlands sports complex.

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Quarterback Donovan McNabb is unlikely to play in Philadelphia’s game against the New York Giants on Sunday because of a groin injury.

“I wouldn’t bet on it,” Eagle Coach Andy Reid said when asked if McNabb could start. “He doesn’t look good today.”

McNabb injured his groin while trying to tackle Dallas’ Roy Williams after throwing an interception. Williams returned it 46 yards for a touchdown with 2:43 left to lead the Cowboys to a 21-20 comeback victory over the Eagles on Monday night.

Reid said McNabb had an MRI and was waiting to see a specialist. If McNabb doesn’t play, Mike McMahon probably would start over Koy Detmer.

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The Arizona Cardinals put injured Pro Bowl defensive end Bertrand Berry and starting guard Reggie Wells on injured reserve, ending their seasons.... New England Patriot center Dan Koppen is out for the season after injuring his shoulder against Miami.... Minnesota Viking quarterback Daunte Culpepper had surgery to repair three torn ligaments in his right knee.