Gene is linked with breast cancer
From Times Staff and Wire Reports
Michigan researchers have identified a gene that is associated with an aggressive form of breast cancer.
They reported Thursday in the journal Cell that the gene, called FOXP3, suppresses the activity of another gene, HER-2, that is commonly found in aggressive tumors. When one copy of the FOXP3 gene is silenced in mice, 90% of the animals develop breast cancer. Researchers found the mutated form of the gene in 80% of samples taken from human breast tumors.
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