Prop. 14 stem cell bond holding onto lead

Alysia Padilla-Vaccaro stands with her 8-year-old daughter, Evangelina Vaccaro, who was born with no immune system.
Alysia Padilla-Vaccaro stands with her 8-year-old daughter, Evangelina Vaccaro, who was born with no immune system and a disorder commonly known as bubble baby disease. A previous stem cell bond measure in California helped pay for Evangelina’s treatment.
(Irfan Khan / Los Angeles Times)

A ballot measure to authorize $5.5 billion in new funding for stem cell research continued to hold its lead early Wednesday.

Proposition 14 asked voters to approve an infusion of cash for the California Institute for Regenerative Medicine, known as CIRM, for stem cell studies and trials. California voters created CIRM in 2004 after approving a bond measure that year for $3 billion. CIRM used that bond money for research grants, new laboratories and training programs, but unallocated funds ran out last year, prompting supporters of the agency to return to taxpayers for additional money.

Results for the measure had yet to be called as of Wednesday morning. Proposition 14 received significant support in coastal counties in the state.


Proponents raised more than $16 million to fill airwaves with stories of successful treatments stemming from the first bond measure. The largest funder of the supporting campaign was real estate investor Robert Klein, who drafted the previous ballot measure and went on to be CIRM’s first chairman — a move that sparked criticism from lawmakers.

CIRM’s creation in 2004 was largely a state effort to counter then-President George W. Bush’s decision to cut off federal funding for stem cell research amid religious opposition to using human embryonic stem cells. Under the 2004 measure, Proposition 71, California created a state constitutional right to conduct stem cell research.

Religious objections to this year’s bond measure were largely absent, with little organized opposition or cash thrown into fighting Proposition 14. However, newspaper editorial boards, including those at the Los Angeles Times and San Francisco Chronicle, opposed the measure. Opponents included CIRM board member Jeff Sheehy, who argued that the state shouldn’t take on new debt while facing deficits due to the COVID-19 pandemic.

With interest, Proposition 14 will cost the state $260 million per year, or $7.8 billion over the next 30 years, according to the nonpartisan Legislative Analyst’s Office. The state is still paying off the $3-billion stem cell bond from 2004, which will cost an additional $3 billion in interest.

Supporters of the measure said the bond will fill a void in crucial grant funding that could lead to new treatments and cures for chronic diseases and conditions, including cancers, spinal cord injuries, Alzheimer’s, Parkinson’s and heart disease. They say the 2004 bond advanced research and treatments for more than 75 diseases, including two cancer treatments for fatal blood disorders that were approved by the U.S. Food and Drug Administration.