Robin Williams is Dave’s second guest | 1993
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Memorable moments on ‘Late Show With David Letterman’

Robin Williams is Dave’s second guest | 1993
Robin Williams on the second taping of the show on Aug. 31, 1993.  (Alan Singer / CBS)
Vice President Al Gore puts regulation to the test | 1993
Vice President Al Gore illustrates the complex federal regulations behind government-purchased ashtrays by cracking one with a hammer on Sept. 8, 1993.  (Alan Singer / CBS)
Drew Barrymore bares it all | 1995
Drew Barrymore turns to the audience after flashing Letterman on his birthday on April 12, 1995.  (Alan Singer / CBS)
David Bowie performs | 1995
David Bowie performs on Sept. 25, 1995.  (Alan Singer / CBS)
Howard Stern in drag | 1995
In perhaps his most memorable appearance on the show, Howard Stern appears in full drag on Dec. 20, 1995.  (Alan Singer / CBS)
Demi Moore shows her strength | 1996
Leading to the release of her 1997 movie “G.I. Jane,” Demi Moore performs feats of strength for the camera on July 2, 1996.  (Alan Singer / CBS)
Dave gets a new look | 1996
Dennis Rodman gives Letterman a new look on Aug. 20, 1996.  (Alan Singer / CBS)
Tina Turner sings the blues | 1997
Tina Turner performs “Undercover Agent for the Blues” on Feb. 24, 1997.  (Alan Singer / CBS)
Simon & Garfunkel, reunited | 2003
Simon & Garfunkel perform on Sept. 12, 2003. This was the first time the two had performed on “Late Show” together, and their first television performance since they had reunited at the 45th Grammy Awards in February 2003.  (Jeffrey R. Staab / CBS)
Dave Letterman’s son is born | 2003
Letterman holds up a photo of his new son, Harry Joseph Letterman, who was born at 11:58 p.m. on Nov. 3, 2003.  (John Paul Filo / CBS)
A ‘sleeping’ Steve Martin | 2003
Steve Martin, left, feigns sleep after asking Letterman to tell him about his new baby on Dec. 22, 2003.  (John Paul Filo / CBS)
U2 performs all week | 2009
U2 performs on the show every night from March 2-6, 2009. This was the first time a band had performed five consecutive nights on the CBS late-night broadcast.  (Jeffrey R. Staab / CBS)
Paul McCartney on the marquee | 2009
Paul McCartney performs on the marquee of the Ed Sullivan Theater on “Late Show With David Letterman” on July 15, 2009.  (Jeffrey R. Staab / CBS)
Chatting with President Obama | 2009
President Obama talks with Letterman on Sept. 21, 2009.  (John Paul Filo / CBS)
Jay, Oprah and Dave watch the big game | 2010
Jay Leno, left, Oprah Winfrey and David Letterman watch the big game together in a special surprise “Late Night With David Letterman” promo, broadcast during CBS Sports’ coverage of Super Bowl XLIV.  (Worldwide Pants Inc. / Worldwide Pants Inc.)
De Niro and Hoffman hug it out | 2010

Academy Award-winning actors Dustin Hoffman, left, and Robert De Niro share a personal moment on Dec. 17, 2010. While this was Hoffman’s seventh visit to the show, this marked the first time De Niro had sat down for an interview with Letterman.

 (John Paul Filo / CBS)
Spiderman drops in for a visit | 2011
U2‘s the Edge, left, Bono and Letterman watch as Spiderman drops in for a visit on July 18, 2011.  (John Paul Filo / CBS)
Selfie surprise with Bill Murray and Lady Gaga | 2014
“Late Night” guests Lady Gaga and Bill Murray, center, take a selfie with Letterman. Lady Gaga invited the entire audience over to the Roseland Ballroom for a special performance.  (Jeffrey R. Staab / CBS)
Foo Fighters and Rick Nielsen | 2014
Foo Fighters perform with special guest Rick Nielsen on Oct. 16, 2014.  (Jeffrey R. Staab / CBS)