Danny Wilson scored early in the second half and the Colorado Rapids handed Los Angeles FC its second loss of the season, 1-0 in a game played in the rain on Friday night.
Colorado (5-9-4) extended its undefeated streak to seven matches. Los Angeles (11-2-4) had its undefeated run halted at eight games.
Wilson headed in a corner kick by Jack Price in the 49th minute. Colorado nearly made it 2-0 in the 84th, but Lee Nguyen cleared it off the line.
Los Angeles' Carlos Vela, the league leader with 16 goals, had his five-game scoring streak halted. LAFC hadn't played since June 1, due to the Gold Cup.