The gated property, called El Castillo, includes more than 4,000 square feet of living space, an elevator, hand-carved living room ceilings, an eat-in kitchen, four bedrooms and four bathrooms
Designed for entertaining, the 1985 Spanish-style house has outdoor entertaining space and a spa.
Krumholtz, 32, starred in the CBS crime drama from 2005 to 2010. He also appeared in the films "Harold & Kumar Escape From Guantanamo Bay" (2008), "Harold & Kumar Go to White Castle" (2004) and "The Santa Clause" (1994).
He bought the house in early 2010 for $2,025,000, according to public records.
Allyson Carter of Rodeo Realty is the listing agent.