Ernie Els withdrew from the Players Championship on Tuesday after injuring his right wrist two weeks ago while working out with a punching bag at his home in London.
Els has already won four times this year. His announcement came a day after Phil Mickelson withdrew because his wife recently gave birth to their third child.
"Obviously, I'm disappointed I couldn't play this week at the Players," Els said. "But given the soreness I felt earlier today, I knew there was no way I could play this week."
Els is expected to play in two week at the Masters.
He played in the Bay Hill Invitational and had a seven-under 65 in the second round to get into contention. His wrist flared up again Saturday, however, and he finished 19 strokes off the lead.
Els said he only recently started using a punching bag as part of his workout routine.
"I'll probably strap my wrists next time," he said.