U.S. clears Novavax vaccine for use as COVID-19 booster

A vial of the COVID-19 vaccine made by Novavax
A vial of the COVID-19 vaccine made by Novavax. The United States has authorized the vaccine to be used as a first booster shot.
(Alastair Grant / Associated Press)

U.S. regulators on Wednesday authorized a booster dose of the COVID-19 vaccine made by Novavax.

The Food and Drug Administration said the new booster option is for people 18 and older who can’t get the Omicron-targeting boosters from Pfizer-BioNTech or Moderna for medical or accessibility reasons — or who otherwise would not receive a COVID-19 booster shot at all.

The FDA specified the additional Novavax shot was to be used as a first booster — not for people who’ve already had one or more booster doses already — at least six months after completing their primary shots.


Novavax’s initial two-dose shots have been available since the summer. Novavax is a protein-based vaccine unlike the other COVID-19 vaccines available in the United States from Pfizer, Moderna or Johnson & Johnson.

Newfangled COVID-19 vaccines have left many people yearning for an old-school alternative. The one from Novavax could fit that bill.

May 16, 2022

About 48% of Americans who received their primary vaccinations have never received that all-important first booster.

“Offering another vaccine choice may help increase COVID-19 booster vaccination rates for these adults,” Novavax Chief Executive Stanley Erck said in a statement.

The Centers for Disease Control and Prevention also signed off on the Novavax boosters.

U.S. health officials have been encouraging Americans to get those updated Pfizer and Moderna boosters to bolster protection against the most common Omicron strain, known as BA.5, ahead of an expected winter surge.

The new Novavax booster is made with that company’s original formula. An Omicron-targeted recipe is still being tested.