Osher, who oversaw Sony Pictures Animation and visual effects unit Imageworks, is leaving to "pursue other interests," according to an internal memo from Sony Pictures Entertainment Chairman Michael Lynton.
This comes just two days after veteran film executive Tom Rothman was named as Sony's next film group president, replacing Amy Pascal, who was forced out this month.
Under Osher, Sony's animation division launched franchises including "Cloudy With a Chance of Meatballs," "Smurfs" and
Osher has led Sony Pictures Digital Productions since 2009, after serving as chief operating officer of the Columbia Pictures Motion Picture Group since 2004.
Sony Pictures Animation was part of the digital productions division until this year. In January, Kristine Belson was named president of the animation arm.
"I want to thank Bob for his 11 years of service and acknowledge the important role he played in strengthening the financial and operational foundation of SPDP," Lynton said in the memo, which was obtained by The Times.
Seperately, Lynton laid out a reorganization of the digital unit to "increase collaboration across the studio."
Imageworks will now be part of the Motion Picture Group. In addition, other units, including post production services, will be aligned with the movies group and Sony Pictures Television.
SPDP will be led by its Executive Vice President Randy Lake.