Jeff VanHorne kicked a 44-yard field goal on Pittsburgh's first possession and Billy Owens returned a last-minute interception 69 yards for a score as the Panthers surprised No. 15 Penn State, 10-0, Saturday night.
Pitt running back Craig Heyward gained 160 yards, his 10th consecutive 100-yard game this season, as the Panthers beat the Nittany Lions in Pitt Stadium for the first time since 1965 and shut them out for the first time since 1955.
Trailing 3-0, Penn State moved to the Pitt 37 with 35 seconds left, but Owens intercepted a pass by Matt Knizner and ran it back for the clinching touchdown.
Pitt (7-3) damaged Penn State's hopes of going to the Florida Citrus Bowl. Penn State (7-3) plays Notre Dame next Saturday.
Pitt blocked two field-goal attempts by Ray Tarasi to record its second straight shutout and third of the season. The Panthers also improved their chances of receiving their first bowl bid since 1983. Scouts from 10 bowls attended the game.