Juicy questions come wrapped in chewy textures on “Love This Giant,” an album-length collaboration between David Byrne and St. Vincent. He’s the deadpan eccentric frontman for Talking Heads; she’s a sly singer-guitarist (born Annie Clark) beloved by brainy indie types. Acquainted through mutual friends in the New York rock scene, the two first teamed up at the behest of Housing Works, a Big Apple bookstore that previously paired Björk with Brooklyn’s Dirty Projectors for a one-off benefit gig. Yet “Love This Giant” quickly outgrew its impetus: In these 12 songs — built on voice and guitar but generously appointed with bright brass arrangements and funky machine beats — Byrne and Clark sound like psychosocial explorers setting out on an open-ended quest. Greek Theatre, 2700 N. Vermont Ave., L.A. 7:30 p.m. Sat. $35 to $75. greektheatrela.com.