Senior Matt Muehlebach tied his career high with 22 points Saturday as Pacific 10 Conference champion Arizona routed Oregon, 107-65, at Tucson.
The ninth-ranked Wildcats (26-6 overall, 14-4 in the Pac-10) increased their home winning streak to 64 games and avenged a setback at Oregon (13-15, 8-10) last week.
Terrell Brandon scored 27 points for Oregon.
Jamal Faulkner and Dwayne Fontana added 14 points each for Arizona State (19-9, 10-8), which hopes to land its first NCAA tournament berth since 1981.
Teo Alibegovic scored 21 points, Mario Jackson added 16 points and Chad Scott had 14 points and 12 rebounds for Oregon State (14-14, 8-10).