49ers...10 Bills...3

For a 49ers team that didn’t have much to play for, linebacker Patrick Willis and a sturdy San Francisco defense certainly did their job as spoilers.

Willis had 14 tackles and forced a fumble in a 10-3 win over Buffalo that all but ended the Bills’ dwindling playoff hopes. The 49ers’ win also prevented the Arizona Cardinals from clinching the NFC West and their first playoff berth in 10 years -- the longest active playoff drought in the NFL.

Isaac Bruce scored on a 12-yard touchdown reception -- the 90th of his career -- and Joe Nedney kicked a 50-yard field goal as the 49ers never trailed. San Francisco (4-8) won for the second time in three games and second time under interim Coach Mike Singletary.

The Bills (6-6) lost for the fifth time in six games and looked nothing like the team coming off a 54-31 win at Kansas City, or the team that got off to a 4-0 start.

Quoteworthy: “It’s going to be hard to sleep and hard to get this taste out of your mouth.” -- Chris Kelsay, Bills defensive end