Why ‘herd immunity’ can’t save us from COVID-19
For a term that’s at least 100 years old, “herd immunity” has gained new life in 2020.
It made headlines last month when reports surfaced that Dr. Scott Atlas, a member of the White House Coronavirus Task Force and advisor to the president, recommended it as a strategy to combat COVID-19. Atlas, a former chief of neuroradiology at Stanford who now focuses on healthcare policy, suggested the virus should be allowed to spread through the population so that people build up immunity, rather than trying to contain it through shutdown measures, according to the Washington Post.
At a town hall event a few weeks later, President Trump raised the idea himself, saying the coronavirus would simply “go away,” as people developed “herd mentality” — a slip-up that was understood to be a reference to the same concept.
And as recently as last week, Sen. Rand Paul (R-Ky.) sparked a heated debate at a committee hearing when he suggested that the decline in COVID-19 cases in New York City was due to herd or community immunity rather than public health measures, such as wearing masks and social distancing. Dr. Anthony Fauci, the top U.S. infectious disease official, rebuked Paul, pointing out that only 22% of the city’s residents have coronavirus antibodies.
“If you believe 22% is herd immunity, I believe you’re alone in that,” Fauci told the senator.
Paul isn’t the only one who’s confused about herd immunity. Here’s a look at whether it can be used to combat COVID-19.
What is herd immunity?
Herd immunity, also called community or population immunity, refers to the point at which enough people are sufficiently resistant to a disease that an infectious agent is unlikely to spread from person to person. As a result, the whole community — including those who don’t have immunity — becomes protected.
People generally gain immunity in one of two ways: vaccination or infection. Vaccines have been the route to herd immunity for most diseases in recent history, including smallpox, polio, diphtheria and rubella.
For the most highly contagious diseases, like measles, about 94% of the population needs to be immunized to achieve that level of protection. For COVID-19, scientists estimate the percentage falls between 50% to 70%.
Can we speed up herd immunity to end the pandemic?
Before the COVID-19 pandemic, experts can’t recall an example in which governments intentionally turned to natural infection to achieve herd immunity. Generally, such a strategy could lead to widespread illness and death, said Dr. Carlos del Rio, an expert in infectious disease and vaccines at the Emory University School of Medicine.
“It’s a terrible idea,” Del Rio said. “It’s basically giving up on public health.”
The U.S. still has a long way to go to achieve herd immunity to the coronavirus that causes COVID-19. A large study published last week in the medical journal Lancet found that fewer than 1 in 10 Americans have antibodies to SARS-CoV-2, the formal name for the coronavirus. Even in the hardest-hit areas, like New York City, estimates of immunity among residents are about 25%.
Israeli scientists say they can mimic the effects of a vaccination campaign if certain people willingly get infected with the coronavirus and recover.
To reach 50% to 70% immunity would mean about four times as many people getting infected and an “incredible number of deaths,” said Josh Michaud, associate director of global health policy at the Henry J. Kaiser Family Foundation. Some of those who survive could suffer severe consequences to their heart, brain and other organs, potentially leaving them with lifelong disabilities.
“It’s not a strategy to pursue unless your goal is to pursue suffering and death,” Michaud said.
Is natural immunity better than a vaccine?
Some scientists say natural immunity may not be a feasible defense against COVID-19.
Although most people presumably achieve some degree of protection against the coronavirus after being infected once, cases of people who recovered from COVID-19 and were reinfected have raised questions about how long natural immunity lasts and whether someone with immunity could still spread the virus.
In exploring coronavirus immunity as the nation reopens, scientists still want to know how long immunity lasts and whether it protects everyone equally.
Even the method scientists are using to measure immunity — blood tests that detect antibodies to the coronavirus — may not be an accurate indicator of who is protected against COVID-19, said Dr. Stuart Ray, an infectious disease expert at the Johns Hopkins University School of Medicine.
With so many unanswered questions, “we can’t count on natural herd immunity as a way to control this epidemic,” he said.
Vaccines, on the other hand, can be made to trigger stronger immunity than natural infection, Ray said. That’s why people who acquire a natural tetanus infection, for example, are still advised to get the tetanus vaccine.
The hope is that vaccines being developed for COVID-19 will provide the same higher level of immunity.
But what about Sweden?
In the political debate around COVID-19, proponents of a natural herd immunity strategy often point to Sweden as a model. Although the Scandinavian country imposed fewer economic shutdown measures, its death rate is less than that of the U.S., Paul said at Wednesday’s Senate hearing.
Sweden’s relatively low-key approach to coronavirus lockdowns captured the world’s attention, but the strategy’s effectiveness remains unclear.
But health experts — including Fauci during the same hearing — said that’s a flawed comparison.
The U.S. has a much more diverse population, with vulnerable groups like Black and Latino Americans being disproportionately affected by the coronavirus, said Dr. Jon Andrus, an epidemiology expert at the George Washington University Milken Institute School of Public Health. The U.S. also has greater population density, especially on the coasts, he said.
When compared with other Scandinavian countries, Sweden’s death toll is much higher. It has had 5,880 deaths linked to COVID-19 so far, according to data from Johns Hopkins University. That’s nearly 58 deaths per 100,000 residents — several times higher than the death rates of 5 or 6 per 100,000 in Norway and Finland.
Despite that level of loss, it’s still unclear if Sweden has reached the threshold for herd immunity. A study by the country’s public health agency found that by late April only 7% of residents in Stockholm had antibodies for COVID-19. In other Swedish cities, the percentage was even lower.
The global COVID-19 death toll surpassed 1 million, one measurement of a scourge that has ravaged lives and economies and evoked an era of plagues.
Those findings mirror other studies around the globe. In several cities across Spain, Switzerland and the U.S. — with the exception of New York City — less than 10% of the population had coronavirus antibodies by June, according to a study in JAMA Internal Medicine. And that was despite months of exposure and high infection rates.
The results led commentators in the Lancet to write, “In light of these findings, any proposed approach to achieve herd immunity through natural infection is not only highly unethical, but also unachievable.”
So what’s the bottom line?
Natural herd immunity is an uncertain strategy, and attempts to pursue it could result in a slew of unnecessary deaths, medical experts say. A vaccine, whenever one becomes available, would offer a safer route to community-wide protection.
Until then, they emphasize there is still plenty to do to counter the pandemic. Wearing masks, practicing social distancing, hand-washing and ramping up testing and contact tracing have all proved to help curb the virus’ spread.
“As we wait for new tools to be added to the toolbox,” Andrus said, “we have to keep reminding ourselves that there are measures in this very moment that we could be using to save lives.”
KHN reporter Victoria Knight contributed to this article.