Nate Stanley threw for 226 yards and five touchdowns, and Iowa throttled sixth-ranked Ohio State 55-24 on Saturday, dealing what's likely to be a fatal blow to the Buckeyes' playoff hopes.
Josh Jackson added three interceptions for the Hawkeyes (6-3, 3-3), who beat their fourth top-five opponent in their last five tries at home.
Iowa raced out to a 31-17 halftime lead on a pair of Stanley TD passes to Noah Fant.
Stanley, following a successful and highly unusual fake field goal, later fired a two-yard TD pass with a defender hanging onto his foot that put the Hawkeyes ahead 38-17 late in the third quarter.
J.T. Barrett threw a career-high four interceptions for Ohio State (7-2, 5-1), which allowed its most points in a game under coach Urban Meyer.
The Buckeyes committed nine penalties and gained just 371 yards in their most lopsided defeat since last year's 31-0 loss to eventual national champion Clemson in the playoff.
No. 24 Michigan State 27, No. 7 Penn State 24: Matt Coghlin kicked a 34-yard field goal as time expired to give the Spartans the upset victory in a game that was delayed nearly 3 1/2 hours by severe weather in the second quarter.
Brian Lewerke threw for 400 yards and two touchdowns for the Spartans (7-2, 5-1 Big Ten), and Michigan State was aided at the end by a roughing the passer call on Penn State's Marcus Allen. Lewerke was hit by Allen on a third-down pass that fell incomplete in the final minute. The penalty moved the ball to the Penn State 22, and the Spartans were able to run the clock down before Coghlin's winning kick.
The redshirt freshman made the kick, then ran back down the field and slid across it on his stomach while his teammates joined him in celebration.
It was the second straight tough loss for Penn State (7-2, 4-2), which fell 39-38 at Ohio State last weekend and may have had its national title hopes crumble for good Saturday. Now it's Michigan State — which went 3-9 last season — that will take its improbable division title hopes into a showdown at Ohio State next weekend.
at No. 1 Georgia 24, South Carolina 10: Jake Fromm proved he can throw as his two touchdown passes led the Bulldogs to the win.
Fromm, who was told “he can’t pass” by a Gamecock, was accurate and efficient, completing 16 of 22 passes for 196 yards with scoring passes of 10 yards to Javon Wims and 20 yards to Mecole Hardman. He did not throw an interception.
Georgia (9-0, 6-0 Southeastern Conference, No. 1 College Football Playoff) has won its first nine games for the first time since 1982. The Bulldogs needed a Mississippi win over Kentucky on Saturday to clinch a spot in the SEC championship game.
South Carolina (6-3, 4-3) had its three-game winning streak snapped. The Gamecocks also lost hopes for winning the SEC East.
at No. 2 Alabama 24, NO. 19 Louisiana State 10: Jalen Hurts passed for a touchdown and ran for a score and the Crimson Tide 9-0, 6-0 Southeastern Conference) sweated out a bruising win over the Tigers.
The Tigers (6-3, 3-2) kept getting defensive stops in the fourth quarter but couldn't muster a threat. They had to punt twice and then managed to squeeze out only a couple of first downs after taking over at their own 8 with 4:39 left.
Quarterback Danny Etling completed a couple of short passes and gave way to backup Myles Brennan, who couldn't push them much further. He was sacked on fourth-and-long by freshman linebacker Dylan Moses.
Alabama ran out the clock on its seventh straight win in the SEC West rivalry.
at No. 3 Notre Dame 48, Wake Forest 37: Brandon Wimbush passed for a career-high 280 yards, ran for two touchdowns as the Irish won their seventh straight in a game in which Irish running back Josh Adams missed the second half because of a concussion.
Wimbush returned for the second half while Adams rode a stationary bike on the sideline as the Irish (8-1) totaled season highs in passing (340) and total yards (720) to set up a showdown with No. 10 Miami.
No. 4 Clemson 38, No. 20 North Carolina State 31: Tavien Feaster ran for an 89-yard touchdown to end the third quarter and K'Von Wallace picked off Ryan Finley on the game's final play to help the Tigers hold off the Wolfpack
Feaster's break-loose run up the middle and gave Clemson (8-1, 6-1 Atlantic Coast Conferenc) a 31-21 lead entering the fourth, then the Tigers had to hang on in the final seconds as the Wolfpack (6-3, 4-1) got one more shot to tie the game in the final minute.
No. 5 Oklahoma 62, at No. 11 Oklahoma State 52: Baker Mayfield passed for a school-record 598 yards and the Sooners outlasted the Cowboys in one of the highest-scoring games in the history of the rivalry.
Mayfield threw five touchdown passes and ran for another score to outduel Oklahoma State's Mason Rudolph in a battle of two Heisman Trophy contenders. Rudolph passed for 448 yards and five touchdowns, but he had three turnovers in the second half.
Marquise Brown caught nine passes for a school-record 265 yards, and he had touchdown receptions of 84 and 77 yards for the Sooners (8-1, 5-1 Big 12). Oklahoma gained 785 total yards.
Oklahoma State (7-2, 4-2) appeared to have lost its last chance when Oklahoma's Tre Brown intercepted the ball off a deflection with 1:56 remaining and the Cowboys trailing 55-52. A targeting penalty against Oklahoma's Will Johnson negated the play, but the Cowboys couldn't take advantage of the extra opportunity.
at No. 8 Texas Christian 24, Texas 7: Kyle Hicks ran for two touchdowns and TCU rebounded from its only loss, staying tied for the Big 12 lead and in contention for a playoff spot.
In a game dominated by two of the Big 12's best defenses, Hicks had 41 yards rushing on 11 carries. That included his 1-yard TD to end TCU's opening drive and his 14-yarder that put the Horned Frogs (8-1, 5-1 Big 12) up 17-0 early in the second quarter. Texas (4-5, 3-3) managed only 263 total yards in its biggest losing margin in coach Tom Herman's first season.
No. 9 Wisconsin 45, at Indiana 17: Jonathan Taylor rushed for 183 yards and a touchdown and Alec Ingold had three scores to help the Badgers pull away to the easy win.
The Badgers (9-0, 6-0 Big Ten) extended the nation's second-longest winning streak to 10 and their school record for consecutive Big Ten victories to 12. They also remained one of a handful of unbeaten teams in the Football Bowl Subdivision. A win next week would give Wisconsin the West Division title and its fifth ticket in seven years to the conference championship game.
at No. 10 Miami 28, No. 13 Virginia Tech 10: Malik Rosier threw two touchdown passes and ran for another score, Travis Homer had a 64-yard touchdown run and the Hurricanes moved to the brink of clinching what would be its first spot in an Atlantic Coast Conference championship game.
Braxton Berrios and Christopher Herndon IV had touchdown catches for Miami (8-0, 6-0 ACC, No. 10 CFP), which extended the nation's longest current winning streak to 13 games.
Virginia Tech (7-2, 3-2) got a touchdown run from quarterback Josh Jackson. He was 20 of 32 passing for 197 yards and two interceptions.
No. 14 Auburn 42, at Texas A&M 27: Jarrett Stidham threw for 268 yards and three touchdowns and the Tigers pulled away in the second half. Kerryon Johnson added 145 yards rushing and a touchdown and provided a highlight-reel play with a nifty one-handed catch for an 11-yard gain on third down in the fourth quarter. Eli Stove capped that possession with a four-yard touchdown run that pushed the lead to 42-20.
Auburn (7-2, 5-1 Southeastern Conference) led by eight at halftime and made it 28-13 when Stidham connected with Ryan Davis on a four-yard touchdown reception early in the third quarter.
The Aggies (5-4, 3-3) were forced to punt on their next drive and Shane Tripucka, who had a punt blocked for a touchdown in the first half, didn't get this one off cleanly and it went just 16 yards to give Auburn good field position.
at West Virginia 20, No. 15 Iowa State 16: Will Grier threw two touchdown passes, Justin Crawford broke out of a three-game slump with 102 yards rushing for the Mountaineers.
West Virginia (6-3, 4-2 Big 12) became bowl eligible and knocked the Cyclones (6-3, 4-2) out of a four-way tie for first place. Iowa State trailed 20-0 late in the second quarter and never recovered in losing on the road for the first time.
at No. 16 Mississippi State 34, UMass 23: Nick Fitzgerald ran for 135 yards and two touchdowns to lead the Bulldogs.
Mississippi State (7-2) trailed 20-13 at halftime, but scored two quick touchdowns in the third quarter to take a 27-20 advantage. UMass (2-7) pulled to 27-23 on a short field goal in the fourth quarter, but couldn't move the ball in the final minutes.
No. 18 Central Florida 31, at Southern Methodist 24: McKenzie Milton threw a touchdown pass and ran for a score, Adrian Killins Jr. rushed for two more touchdowns and UCF stayed undefeated.
The Knights (8-0, 5-0 AAC) remained the only undefeated team in the Group of Five, keeping them on track to play in a major New Year's Day bowl game if they can win out.