Old newspaper boxes are being used to distribute the overdose reversal drug naxolone
For decades, Jeff Card’s family company was known for manufacturing the once ubiquitous tin boxes where people could buy newspapers on the street.
Today, reach into one of his containers and you may find something entirely different and free of charge: Naloxone, the opioid overdose reversal drug.
Naloxone distribution containers have been proliferating across the country in the more than a year since the U.S. Food and Drug Administration approved its sale without a prescription. Naloxone, a nasal spray most commonly known as Narcan, is used as an emergency treatment to reverse drug overdoses.
Such boxes — appearing in neighborhoods, in front of hospitals, health departments and convenience stores — are one way those supporting people with substance use disorder have sought to make Narcan, which can cost around $50 over the counter, accessible to those who need it most. Not unlike little free libraries that distribute books to anyone who wants one, the metal boxes used formerly as newspaper receptacles aren’t locked and don’t require payment. People can take as much as they think they need.
Advocates say the containers help normalize the medication — and are evidence of steadily reducing stigma around its use.
Researchers at Stanford and elsewhere identified a compound that, when tested on mice, enhanced naloxone opioid-overdose-reversing effect and lessened withdrawal symptoms.
Sixty Narcan receptacles were distributed across 35 states in honor of Thursday’s “Save a Life Day” — a naloxone distribution and education event started by a West Virginia nonprofit in 2020. Containers were purchased from Card’s Texas-based Mechanism Exchange & Repair, which still serves newspaper customers but has expanded to manufacturing other products amid the newspaper industry’s decline.
“It’s fortunate and unfortunate,” said Card, who started making the Narcan containers over two years ago. “Fortunate for us that we’ve got something to build, but unfortunate that this is what we have to build, given how bad the drug problem is in America.”
Opioid deaths were already at record levels before the COVID pandemic, but they skyrocketed when it hit in early 2020. The U.S. Centers for Disease Control and Prevention estimated there were about 85,000 opioid-related deaths in the 12 months that ended in April 2023. But since then, they fell. The CDC estimate for the 12 months that ended in April 2024 was 75,000 -- still higher than any point before the pandemic.
A new bill would require California workplaces to stock a nasal spray that can prevent opioid overdoses, greatly expanding the range of locations that have the lifesaving medication on hand.
The reasons for the decline are not fully understood. But it does coincide with Narcan, a medication that’s been hard to get in some communities, becoming available over the counter, as well as with the ramping up of spending of funds from legal settlements between governments and drugmakers, wholesalers and pharmacies.
The FDA approved Narcan to treat overdoses back in 1971, but its use was confined to paramedics and hospitals for decades. Narcan nasal spray was first approved by the FDA in 2015 as a prescription drug, and in March it was approved for over-the-counter sales and started being available last September at major pharmacies.
“That took the barriers away. And that’s when we realized, ‘OK, now we need to increase access. How can we get naloxone into the communities?’” said Caroline Wilson, a West Virginia social worker and person in recovery who coordinated this year’s Save a Life Day.
Last year, all 13 states in Appalachia participated in the day, spearheaded by West Virginia nonprofit Solutions Oriented Addiction Response. Community organizations in hundreds of counties set up tables in parking lots outside churches and clinics handing out Narcan and fentanyl test strips and training people how to use them. They also work to educate the public on myths surrounding the medication, including the fallacy that it’s unsafe to have in easily accessible places. Narcan has no effect on people who use it without opioids in their system.
The state and L.A. County have worked hard to make Naloxone more widely available. One of the hurdles, though, has been the price of the inhalable version, Narcan.
This year, with the effort expanding to 35 states and a theme of “naloxone everywhere,” the group sent out 2,000 emergency kits containing one Narcan dose to be placed in locations like convenience store bathrooms or parks. The 60 tin newspaper boxes — which sell for around $350 apiece — were purchased with grants.
Aonya Kendrick Barnett’s harm reduction coalition Safe Streets Wichita installed one of Kansas first Narcan receptacles — which she refers to as “nalox-boxes” — in February. The boxes, now sold by a few different companies, can look different, too. Some look like newspaper boxes, while others look like vending machines.
Since installing a vending machine Narcan container — which just requires a ZIP Code be entered on the keypad to access the medication — it has distributed around 2,600 packages a month.
“To say, ‘Hey, we have a 24-hour vending machine, come over here and come get what you need — no judgment,’ is so bold in this Bible Belt state and it’s helping me break down the the stigma,” she said.
Kendrick Barnett said there’s no place for judgment when it comes to what she calls livesaving healthcare: “People are going to use drugs. It’s not our job to condemn or condone it. It’s our job to make sure that they have the necessary healthcare that they need to survive.”
The Save a Life Day box her organization received is going to go in front of their new clinic, scheduled to open in October.
The FDA has approved over-the-counter sales of opioid overdose antidote naloxone, the first such drug to become available without a prescription.
In Erie, Pa., 74-year-old stained glass artist Larry Tuite said he grew concerned seeing overdoses increasing in his city. He began leaving Narcan packages on the windowsills of 24-hour markets in town that sell products like pipes and cigarette rolling papers. He was shocked at how quickly they disappeared.
“As many as I give out, I run through them really quickly,” said Tuite, who keeps cases of the drugs stacked along the walls of his studio apartment.
The Save a Life Day container, which he got permission to put outside one such store, has helped him to disperse even more Narcan. At least a dozen people have been saved by the medication he’s distributed, he said.
Tasha Withrow, a person in recovery who runs a harm reduction coalition based out of Putnam County, W.Va., said Narcan wasn’t something she ever had access to when she was using opioids.
“People can just reach in and grab what they need — we didn’t have that back then,” she said, while stocking a box in a residential neighborhood earlier this week. “To actually see that there is some access now — I’m glad that we’ve at least moved forward a little bit in that direction.”
Willingham writes for the Associated Press. AP journalist Geoff Mulvihill contributed to this report.
More to Read
Sign up for Essential California
The most important California stories and recommendations in your inbox every morning.
You may occasionally receive promotional content from the Los Angeles Times.