Vandals broke into the Simi Valley Boys & Girls Club over the weekend, splattering paint and scrawling obscenities on the walls, floors and furniture and stealing a tether ball and four fire extinguishers.
The incident occurred at the club's temporary home on Kadota Street on Sunday, Executive Director Becca Merrell said.
It was the latest in a string of mishaps to befall the club, which serves about 2,000 Simi Valley youths.
Three months ago the club was forced out of its permanent building after the Jan. 17 earthquake caused $100,000 in damage.
Sunday's vandalism was the second such incident since the club moved into its temporary quarters, Merrell said.
Several weeks ago vandals knocked over shelves and dumped paint on the floor, Merrell said.
"I feel like we're just getting one hit after another," Merrell said. "Some of the kids really feel upset, like 'Why us? We didn't do anything wrong.' "
An estimate for Sunday's damage is still being compiled, Merrell said, because she is trying to determine whether a pool table that was coated with paint can be salvaged or needs to be replaced.
Police have no suspects, said Sgt. Mike King of the Simi Valley Police Department.
In the meantime, the club is seeking donations of board games, balls and markers, crayons and other arts and crafts materials.
To make a donation, call the club at 527-4437.