Arizona: Larry Fitzgerald’s 2,169 yards and 17 touchdowns against the 49ers are his most vs. any team. He has 515 yards and five TDs in the teams’ last six meetings.
Atlanta: Julio Jones, who leads the NFL in receiving yards with 502, hasn’t scored a touchdown but faces Pittsburgh, which has allowed a league-high 12 scoring passes.
Carolina: Christian McCaffrey rushed for a career-high 184 yards last week. He leads the NFL’s top rushing offense, which faces the Giants’ No. 29 rushing defense.
Chicago: Mitchell Trubisky had a breakthrough game against Tampa Bay last week, throwing for 354 yards and six touchdowns with a passer rating of 154.6.
Dallas: Ezekiel Elliott had a career-high 255 yards from scrimmage (152 rushing, 88 receiving) last week vs. Detroit. He carried a season-high 25 times.
Detroit: Golden Tate, Marvin Jones and Kenny Golladay are the first trio of teammates to each have 50-plus yards receiving in five consecutive games.
Green Bay: Aaron Rodgers is 13-2 against the Lions and 7-1-1, with 23 touchdowns and no interceptions, in his last nine games against NFC North opponents.
Minnesota: The league’s worst rushing attack takes on Philadelphia, which is best in the NFL against the run. Dalvin Cook is the Vikings’ top rusher with 98 yards.
New Orleans: Drew Brees is 201 yards passing from breaking Peyton Manning’s all-time record of 71,940. He faces Washington’s No. 3-ranked pass defense.
N.Y. Giants: Saquon Barkley is looking to join Adrian Peterson and Kareem Hunt as the only players with 100 yards from scrimmage in their first five games.
Philadelphia: Carson Wentz struggled against the Vikings as a rookie in 2016, completing 16 of 28 passes for 138 yards with one touchdown and two interceptions.
RAMS: Todd Gurley, whose 338 yards rushing and 532 total yards are second best in the league, had 152 yards rushing and four TDs in last game vs. Seattle.
San Francisco: C.J. Beathard passed for a career-high 298 yards and tied a personal best of two TD passes last week vs. the Chargers in his first start this season.
Seattle: Seahawks RBs have had consecutive 100-yard games for the first time since 2014. Chris Carson had 102 yards in Week 3 and Mike Davis had 101 last week.
Tampa Bay: The Buccaneers have a bye week to figure out how to fix a defense that gives up a league-worst 34.8 points and second-worst 445.8 yards per game.