The AFC from A to Z:
Baltimore: Receiver Steve Smith is 15 catches short of 1,000 for his career. Quarterback Joe Flacco has won seven of his last nine games against NFC opponents.
Buffalo: Bills defensive tackle Marcell Dareus will make his return from a four-game suspension for his second violation of league's substance abuse policy.
Cincinnati: Running back Jeremy Hill leads the NFL with 23 rushing touchdowns since 2014. Geno Atkins leads all defensive tackles with 42 1/2 sacks since 2011.
Cleveland: Isaiah Crowell is second in the league with 386 yards rushing, most in first four games for Cleveland since Hall of Famer Jim Brown (476) in 1965.
Denver: Linebacker Shane Ray has three sacks and a fumble return for a touchdown since replacing DeMarcus Ware (broken forearm) in Week 2.
Houston: Defensive end Jadeveon Clowney has five sacks in his last eight regular-season games. Receiver Will Fuller has been targeted at least seven times each game.
Indianapolis: The Colts have gone 54 games without a 100-yard rusher. Frank Gore needs 20 yards rushing to pass Jim Brown (12,312) for No. 9 all-time.
Jacksonville: Defensive end Jared Odrick (triceps), linebacker Dan Skuta (hip) and tight end Julius Thomas (elbow) are expected to return after the bye.
Kansas City: Coach Andy Reid is 15-2 following a bye week. Travis Kelce is third among tight ends with 22 catches and sixth with 220 yards receiving.
Miami: The Dolphins rank last in third-down conversions (27%). Their defense on third down ranks second best at 32%. Miami has only one interception.
New England: Tom Brady has the fifth-most passing yards (58,028). He's tied with Peyton Manning with four seasons with 35 or more touchdowns.
N.Y. Jets: Quarterback Ryan Fitzpatrick is 0-4 against the Steelers and leads the NFL with 10 intercepted passes. The Jets' 13 turnovers are the most in the NFL.
Oakland: The Raiders are looking for their first 4-1 start since 2002, when they won the AFC title. A win over San Diego would be their first three-game winning streak since 2011.
Pittsburgh: Receiver Sammie Coates is fourth in the league in yards per catch (21.6). He has at least one reception of 40 yards in each of the Steelers' four games.
San Diego: The Chargers led all four of their games at the two-minute warning in the fourth quarter, but lost three. They were swept by Oakland last season.