Dallas receiver Joey Galloway is out for the season after tests Monday confirmed he tore a knee ligament in the season-opening 41-14 loss to Philadelphia.
Aikman sustained the ninth concussion of his 12-year career against Philadelphia and Cunningham sprained his right thumb.
Dallas will put Galloway on injured reserve and activate rookie quarterback Clint Stoerner from the practice squad.
"Let me be sure we're clear about one thing: I'm not interested in any way of jeopardizing his long-term well-being," Cowboy owner Jerry Jones said of Galloway. "If you think I'm sitting here pushing him to get back out there on behalf of winning a ball game, the answer is no."
Mike McKenzie, the Green Bay Packers' standout second-year cornerback, is expected to be out at least four weeks because of torn cartilage in his left knee.
McKenzie is scheduled for arthroscopic surgery on Wednesday, Packer General Manager Ron Wolf said Monday. McKenzie was apparently injured early in the second quarter of the Packers' season-opening 20-16 loss to the Jets on Sunday.
"We just found about it, so it's a tough blow," defensive coordinator Ed Donatell said. "He was one of the more valuable players on this team last year."
New York Giant safety Sam Garnes will have a post-concussion evaluation today to determine whether he can play Sunday against Philadelphia.
Garnes, injured in the fourth quarter of the Giants' 21-16 victory over Arizona on Sunday, still had lingering headaches and some memory loss after being released from the Hospital for Special Surgery, where he was held overnight for observation.
"Right now I think I probably won't play, but I'm going to fight to the end," Garnes said after returning to Giants Stadium on Monday. "I'm here to play football and I can't have my boys go out there by themselves."
Jacksonville tight end Damon Jones will miss the rest of the season because of a torn anterior cruciate ligament in his right knee, yet another in a string of injuries that continue to plague the Jaguars.
Jones was hurt on the second play of Jacksonville's 27-7 victory over Cleveland on Sunday, when Brown cornerback Daylon McCutcheon hit him around the knee while tackling him near the sideline.
Doctors also diagnosed running back Stacey Mack with a sprained left ankle. He hurt the ankle twice Sunday, and was taken off the field on a cart the second time.
One game into the season, Seattle Coach Mike Holmgren might be ready to make a quarterback change after starter Jon Kitna played poorly in the shutout loss to Miami.
Holmgren said he hasn't made up his mind about who his starter will be in the home opener Sunday against defending Super Bowl champion St. Louis.
It will be either Kitna, who started in the 23-0 loss to the Dolphins, or Brock Huard, who replaced Kitna in the second half.
"We've thought about it a lot and we'll continue to think about it," Holmgren said. "I'll have the decision made by Wednesday. I have not made my decision yet. If we make a change, obviously it's a big decision for the two quarterbacks involved and our team, and I'm not going to be rushed into that. I'm going to think about it a lot."
Running back Stephen Davis' new deal with Washington is the first in league history to have a maximum value of more than $100 million, although realistically it is worth much less.
The Redskins formally announced the deal Monday. Strictly by the numbers, the contract covers nine years at $90.75 million with an extra $45 million available in incentives, making the total possible package worth a staggering $135.75 million.
However, only the $6.5 million signing bonus is guaranteed. The deal is otherwise purposely designed to be renegotiated early and often to keep the team from bursting the salary cap.