Sinopharm COVID-19 vaccines appear safe and effective, study says

A medical worker holds a package of Sinopharm vaccine in Beijing.
A medical worker holds a package of Sinopharm vaccine in Beijing. Two vaccines made by the Chinese firm appear to be safe and effective against COVID-19, according to a new study.
(Mark Schiefelbein / Associated Press)

Two vaccines made by China’s Sinopharm appear safe and effective against COVID-19, according to a study published in a medical journal.

Scientists had been waiting for more details about the two vaccines, even though they already are being used in many countries, and one recently won the backing of the World Health Organization for emergency use.

The report, published online in the Journal of the American Medical Assn., concluded the two vaccines are about 73% and 78% effective, as Sinopharm has previously claimed.


Researchers from Sinopharm and its partners in the Middle East say the trial involved around 40,380 participants and tested the company’s two vaccines — one developed by the Wuhan Institute of Biological Products and the other by the Beijing Institute of Biological Products — against a placebo.

The trial was carried out in four countries — Bahrain, the United Arab Emirates, Egypt and Jordan. However, the study provided data for just Bahrain and the UAE.

The authorization potentially paves the way for millions of the doses to reach needy countries through a U.N.-backed program rolling out vaccines.

May 7, 2021

“There’s nothing very surprising. It’s consistent with what they have claimed previously, but it does not completely eliminate the doubts about Sinopharm,” said Jin Dong-yan, a medical professor at the University of Hong Kong who was not involved with the study.

He raised doubts about how protective the vaccine was based on a recent surge of cases in the island nation of Seychelles, which had vaccinated a large majority of its population with the Sinopharm vaccine.

The study, done mostly in younger men, had little information about the vaccine’s effectiveness against severe disease. Some experts also expressed concern at the shortage of female participants; 85% of the study participants were men.


“It’s important to make sure you have tested it in enough women to be able to start seeing any possible safety concerns,” said Ashley St. John, an associate professor at Duke-NUS Medical School in Singapore.

A spokesperson for the company did not immediately respond to a request for comment.

Sanofi and GlaxoSmithKline have launched a large clinical trial of their COVID-19 vaccine that will enroll 35,000 adult volunteers around the world.

May 27, 2021

The vaccines, both of which are made with inactivated viruses, have already been given to millions of people across the world.

The World Health Organization cleared the Beijing Institute of Biological Products’ shot for emergency use in early May, making it the first Chinese vaccine to receive the certification.

Chinese Foreign Minister Wang Yi said in April that China has provided vaccines to more than 100 countries, although it has not identified them.

While China has six vaccines in use, the majority of its exports come from two companies: Sinopharm and Sinovac.


Wu reported from Taipei, Taiwan.