Jamie Estrada hit a three-run home run with two out in the ninth inning to give Rancho Santiago a 13-10 victory over host Mission in a Southern California regional game Sunday at Mission.
Mission (26-17) was eliminated from the best-of-three series. The Dons (35-11), the defending state champions, advanced to the second round next weekend.
The home run by Estrada, his third hit of the game, came after Mission had tied the game, 10-10, with five runs in the ninth.
Shortstop Erik Lazerus (two for four) drove in the tying run in the ninth with a single to right field.
Estrada, the designated hitter, drove a low fastball from reliever John Romero (5-5) over the center-field fence. Right-hander Kirk Irvine (7-1) pitched the ninth.